Dr. Mahesh B. Palkar

Professor - M.Pharm., Ph.D., Post-Doc

Specialization : Pharmaceutical and Medicinal Chemistry

E mail : mahesh.palkar@nmims.edu

Phone : 022-42332000 (Extn- 2027)

Experience : 21 years 01 month (Academics)

During the tenure of 21 years, Dr. Mahesh Palkar, served mainly in K.L.E. Society’s Pharmacy Institutions at different capacities like Principal, Professor and Head during which major administrative responsibilities like NBA, NIRF, NAAC & PCI were successfully accomplished in addition to his routine academic & research portfolios. Till date, he has successfully guided 17 M.Pharm projects and co-guided 3 Ph.D candidates. He has successfully completed Post-Doctoral Research Fellowship (PDF) at the College of Health Sciences, University of KwaZulu-Natal, Durban (South Africa). He has published more than 50 research articles in peer-reviewed national/ international journals with a cumulative impact factor of more than 140 and his Scopus author h index is 19. Further he has published 2 Indian patents. He has received research grants of worth Rs.30 lakhs from various funding agencies. He has worked as Organizing Secretary in organizing various state level conferences/workshops.

Interest areas:

Rational drug design and development [CADD and Molecular Modelling]
Synthesis various bioactive heterocyclic compounds from Synthetic/Semi-synthetic/Natural leads
Drug-drug and/or drug-excipient interaction studies
Anti-cancer and anti-tubercular drug development
Analytical method development

Research

Publications – Total number 52 (International – 39, National - 12)
Books- Nil
Book Chapters- Nil
Patents- 02 (Published – 2, Granted – 0)
Presentations- Total number 15 (International – 7, National – 8)
Government funded projects – 02 Completed
- Design, synthesis and evaluation of in-vitro enzyme inhibition assay of novel anti-tubercular agents, Research Promotion Scheme (RPS) of AICTE, New Delhi, Rs.14.8 lakhs
- Design, Synthesis, and Biological Evaluation of DNA gyrase inhibitors as Antimicrobial and Anti-tubercular Agents, University of KwaZulu-Natal of South Africa, Rs.15.6 lakhs
Industry projects : Nil

Conferences/Workshops/Seminars – Attended: 43; Organized: 06; Scientific Sessions Co-chaired: 02

Academic activities

He has successfully guided 17 no. of M.Pharm. students for their research projects.

He has successfully co-guided 3 no. of Ph.D. scholars.

Awards/Honors/Recognition:

Recognized as Co-chairperson and Poster Evaluator for a scientific session at SERB, DST, Govt. of India sponsored national conference on "Nanomedicine and Artificial Intelligence: Past, Present and Future” held at SVKM’s NMIMS, School of Pharmacy & Technology Management, Shirpur, Maharashtra, on 23^rd and 24^th July 2022.
Worked as Organizing Secretary in organizing 60^th National Pharmacy Week-2021 in association with Karnataka State Pharmacy Council (KSPC), Bengaluru, from 22^nd to 26^th November 2021.
Worked as Organizing Secretary in State Level Workshop entitled "Recent Trends in Cosmetology” conducted at Jagadaguru Tontadarya Science College, Gadag on 15^th February 2020.
Received the annual prestigious ‘Best Teacher Award’ on eve of Teachers Day-2015 from K.L.E. Academy of Higher Education and Research (KAHER), Belagavi, on 5th September 2015.
Co-chaired a scientific session (Poster) at the 1^st Annual Convention of Karnataka State APTI (KAAPTICON-2015) held at BLDEA’s College of Pharmacy, Vijaypur-586103, Karnataka, on 28^th and 29^th March 2015.
Recipient of Travel Grant for presenting a Research Paper at international conference on High-Performance Computing and Molecular Modeling held in Cape Town International Convention Centre, Cape Town, South Africa, December 2013.
Received Post-Doctoral Research Fellowship (PDRF) from College of Health Sciences, University of KwaZulu-Natal (UKZN), Westville Campus, Durban (South Africa), August 2013.
Recipient of Travel Grant for presenting a Research Paper at EURO-QSAR-2004 held in Istanbul (Turkey), September 2004.
Secured 5^th rank to Rajiv Gandhi University of Health Sciences, Karnataka, Bangalore, in Pharmaceutical Chemistry discipline during M. Pharm. Course, March 2003.
Recipient of silver medal for securing 2^nd rank in B. Pharm. Course from Karnataka University, Dharwad, December 1999.
Qualified in All-India competitive exam Graduate Aptitude Test in Engineering (GATE) March 1999.

Professional Memberships

Registered Pharmacist, Karnataka State Pharmacy Council (KSPC).
Life Member of the Association of Pharmaceutical Teachers of India (APTI).
Expert Member, Board of Studies, Shree Dhanawantry Pharmacy College, Kim, Surat
Member of MCOPS Alumni Association, Manipal University, Karnataka

Recent Publications

Ganai AM, Pathan TK, Mohite SB, Voj´aˇckov´a V, ˇRezníˇckov´a E, Kozlansk´a K, Kryˇstof V, Govender K, Mokoena S, Merugu SR, Palkar MB, Moodley K, Karpoormath R. Design and synthesis of novel 1,2,4-triazolo[4,3-b] pyridazine derivatives with anti-cancer activity. Journal of Molecular Structure 2023, 1291, 135938 https://doi.org/10.1016/ j.molstruc.2023.135938 [Impact factor: 3.841]
Naik SD, Chandavarkar SK, Tawade SS, Shingade SG, Palkar MB, Mamle Desai SN. Docking, synthesis, and characterization of novel heterocyclic ring system and their evaluation for mGlu8 receptor agonist as anticonvulsant agents. Indian Journal of Chemistry 2022, 61B (5), 544 – 550. [Impact factor: 0.543]
Shinde SR, Girase P, Dhawan S, Inamdar SN, Kumar V, Pawar C, Palkar MB, Shinde M, Karpoormath R. A systematic appraisal on catalytic synthesis of 1,3-oxazole derivatives: A mechanistic review on metal-dependent synthesis. Synthetic Communications, 2022, 52 (1), 1-36 https://doi.org/10.1080/00397911.2021. 1989596 [Impact factor: 2.007]
Bolakatti G, Palkar MB, Katagi M, Hampannavar GA, Karpoormath RV, Ninganagouda S, Badiger AM. Novel series of benzo[d]thiazolyl substituted-2-quinolone hybrids: Design, synthesis, biological evaluation and in-silico insights. Journal of Molecular Structure, 2021, 1227, 129413 https://doi.org/10.1016/j.molstruc. 2020.129413 [Impact factor: 3.196]
Girase PS, Dhawan S, Kumar V, Shinde SR, Palkar MB, Karpoormath R. An appraisal of anti-mycobacterial activity with structure-activity relationship of Piperazine and its analogues: A review. J. Med. Chem.2021, 210, 112967 https://doi.org/10.1016/ j.ejmech.2020.112967 [Impact factor: 6.514]
Patel HM, Karpoormath RV, Palkar MB. Exploring MDR‐TB inhibitory potential of 4‐amino quinazolines as tuberculosis N‐acetylglucosamine‐1‐phosphateuridyl transferase (GlmUMTB) inhibitors. Chemistry and Biodiversity. 2020, 17 (8), 237 https://doi.org/10. 1002/cbdv.202000 [Impact factor: 2.408]
Shaikh MS, Chandrasekaran B, Palkar MB, Kanhed AM, Kajee A, Mlisana KP, Singh P, Ghai M, Mahlalela MC, Karpoormath R. Synthesis and biological evaluation of novel carbazole hybrids as promising antimicrobial agents. Chemistry and Biodiversity. 2020, 17 (5), 550 https://doi.org/10.1002/cbdv.201900550 [Impact factor: 2.408]
Priolkar RNS, Shingade S, Palkar MB, Mamle Desai SN. Design, synthesis, characterization of novel linomide analogues and their evaluation for anticancer activity. Current Drug Discovery Technologies 2020, 17(2), 203-212. [Impact factor: 1.720]